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Theun de Groot

Ph.D. degree for Theun de Groot

Theun3 20 Dec 2011

Theun de Groot received his Ph.D. degree in the Medical Sciences of the Radboud University Nijmegen after the successful defense of his thesis entitled 'A terminal view at the epithelial calcium channel TRPV5'. During his PhD research Theun studied the regulation of the epithelial calcium channel that acts as the gatekeeper in renal calcium handling. The calcium concentration in our body is kept constant and is essential for many vital processes like formation of our skeleton, muscle contractions, neuro transmitter release and cellular signalling. Theun identified the mechanisms by which hormones in our body regulate the calcium channel TRPV5, and therefore, the calcium balance. He could demonstrate that the parathyroid hormone phosphorylates and subsequently opens the channel at the plasma membrane of the renal cells. His work underlines the key function of TRPV5 in the maintenance of the calcium balance. Theun continues his work as Post.doc of our department in the group Osmoregulation.

On the occassion of his PhD defence Theun was interviewed by "het Brabants Dagblad".
You can read more about the interview here.


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