Mark Hess M.Sc.
PhD student
- Mark Hess M.Sc.
- +31 (0)24 36 10571
- m.hess@fysiol.umcn.nl
In 2008 Mark started his 1st master-internship medical biology at
our department where he investigated the interaction of the TRPV5
calcium channel and CB28k calcium binding protein, two major
players involved in renal calcium transport. Interested in renal
ion transport, his 1st master thesis dissected the distribution of
potassium transporters in the distal convoluted tubule of the
nephron. In 2009 he performed a 2nd master-internship at MSD
(Organon N.V.) Biological Sterile Product Deveopment. He was
crucially involved in the characterization of the oligomerization
behavior of a biomolecule and he also developed of a parental drug
product formulation of this biomolecule for human. Triggered by
pharmacologic research, his 2nd master-thesis established a
comprehensive model for cellular internalization of cell
penetrating peptides which are potent vectors for drug deliverance.
After his successful graduation in medical biology, in Nijmegen in
2010, he recently rejoined our lab and started his PhD trajectory.
His project aims to clarify the occurrence of hypomagnesemia in
patients which are dependent on the daily intake of proton pump
inhibiting drugs.