Sjoerd Verkaart Ph.D.
Technician
- Sjoerd Verkaart Ph.D.
- +31 (0)24 36 17799
- s.verkaart@fysiol.umcn.nl
Sjoerd Verkaart studied Medical Biology in Nijmegen and
subsequently completed his PhD at the Department of Biochemistry at
the Radboud University Nijmegen Medical Centre in Nijmegen. His PhD
focused on the involvement of reactive oxygen species in the
pathogenesis NADH:ubiquinone oxidoreductase deficiency, a fatal
disease affecting mitochondrial function. At the department of
Physiology, he uses life-cell imaging and patch-clamp analysis to
study the molecular regulation of the epithelial calcium and
magnesium channels TRPV5 and TRPM6.
Related publications
- The identification of histidine-712 as a critical residue for constitutive TRPV5 internalization.
de Groot T, Verkaart S, Xi Q, Bindels RJ, Hoenderop JG.
J Biol Chem 285: 28481-28487, 2010 - The calcium-sensing receptor promotes urinary acidification to prevent nephrolithiasis.
Renkema KY, Velic A, Dijkman HB, Verkaart S, van der Kemp AW, Nowik M, Timmermans K, Doucet A, Wagner CA, Bindels RJ, Hoenderop JG.
J Am Soc Nephrol 20: 1705-1713, 2009 - TRPV5 is internalized via clathrin-dependent endocytosis to enter a Ca2+-controled recycling pathway.
Graaf van de S, Rescher U, Hoenderop JG, Verkaart S, Bindels RJ, Gerke V.
J Biol Chem 283: 4077-4086, 2008
